신경면역 중개연구실

Lab of Translational Neuroimmunology

Hyunwoo Ju, Ph.D.

Research Interests

1. Neuroimmune interactions after stroke and brain injury
2. Mechanisms of monocyte/macrophage modulation and identification of therapeutic targets
3. Crosstalk between peripheral organs (e.g., muscle) and immune function in post-stroke immunity
4. Development of novel therapeutic strategies for neuroinflammation and recovery

Selected Publications

1. Hyunwoo Ju, Joseph Minker, Ina Pavlova, Sunghee Cho, Il-Doo Kim. Acute, not delayed, treatment of aflibercept enhances vessel density in post-ischemic brain and promotes long-term stroke recovery in obese mice. J Cereb Blood Flow Metab. 2025 Jul;45(7):1402-1412. doi: 10.1177/0271678X251330102.
2. Hyunwoo Ju, Il-Doo Kim, Ina Pavlova, Shang Mu, Keun Woo Park, Joseph Minkler, Ahmed Madkoor, Wei Wang, Xiaoman Wang, Zhuhao Wu, Jiwon Yang, Maria Febbraio, John W Cave, Sunghee Cho. Ischemic Conditioning Promotes Transneuronal Survival and Stroke Recovery via CD36-Mediated Efferocytosis. Circ Res. 2025 Feb 28;136(5):e34-e51. doi: 10.1161/CIRCRESAHA.124.325428. (Editor’s Pick, Cover Article)
3. Hyunwoo Ju, Keun Woo Park, Il-Doo Kim, John W Cave, Sunghee Cho. Phagocytosis converts infiltrated monocytes to microglia-like phenotype in experimental brain ischemia. J Neuroinflammation. 2022 Jul 18;19(1):190. doi: 10.1186/s12974-022-02552-5.